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Immunotherapy & CAR-T Cell Therapy Treatment in Mumbai for Nigeria

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Advanced Immunotherapy & CAR-T Cell Therapy in Mumbai for Nigerian Patients

For many Nigerian patients facing complex cancer diagnoses, finding advanced treatments like Immunotherapy and CAR-T Cell Therapy can feel overwhelming. Concerns about treatment access, specialist availability, and financial feasibility often arise when exploring options abroad.

Mumbai has emerged as a preferred destination for international medical care due to its concentration of leading hospitals and specialized oncologists. Patients choose Mumbai for its well-coordinated care pathways and advanced medical infrastructure designed for global visitors.

The city’s medical institutions are renowned for their expertise in innovative cancer therapies, offering world-class facilities and experienced teams. Patients benefit from comprehensive treatment plans and integrated follow-up care within Mumbai’s supportive environment.

Is Mumbai the right choice for your cutting-edge cancer treatment?

What is Immunotherapy and CAR-T Cell Therapy?

Immunotherapy harnesses the body's own immune system to fight cancer. It works by either boosting the immune system's natural ability or by adding immune system components to help destroy cancer cells. CAR-T Cell Therapy is a highly specialized form of immunotherapy. It involves taking a patient's T-cells, genetically engineering them in a lab to produce chimeric antigen receptors (CARs) that can bind to specific proteins on cancer cells, and then infusing these modified cells back into the patient. These CAR-T cells then actively seek out and eliminate cancer cells. Both therapies represent significant advancements in treating certain aggressive cancers, offering new hope where conventional treatments may have limited success.

Considering Immunotherapy or CAR-T Cell Therapy in Mumbai? Connect with our patient support team today.

What are the types of Immunotherapy and CAR-T Cell Therapy?

  • CAR-T Cell Therapy (specifically targeting CD19 for certain blood cancers)
  • Checkpoint Inhibitors (PD-1, PD-L1, CTLA-4 inhibitors)
  • Monoclonal Antibodies (targeting specific cancer cell markers)
  • Oncolytic Viruses (viruses modified to infect and kill cancer cells)
  • Cancer Vaccines (boosting immune response against cancer antigens)
  • Cytokines (immune system proteins that enhance immune responses)

When is Immunotherapy or CAR-T Cell Therapy needed?

  • Diagnosed with certain types of lymphoma, leukemia, or myeloma.
  • Cancer has recurred or progressed after standard treatments like chemotherapy or radiation.
  • Specific genetic markers or mutations indicate potential responsiveness to immunotherapy.
  • Advanced solid tumors that have not responded to conventional therapies.
  • Desire for a targeted treatment approach with potentially fewer side effects than traditional methods.

What evaluation is done before treatment?

  • Comprehensive blood tests including complete blood count, kidney and liver function tests.
  • Imaging scans such as PET CT or MRI to assess cancer spread and tumor characteristics.
  • Biopsy of tumor tissue for genetic profiling and expression of specific immune markers.
  • Cardiac evaluation including ECG and echocardiogram to ensure heart health.
  • Infectious disease screening to rule out active infections.
  • Bone marrow aspiration and biopsy for hematological malignancies.

How are Immunotherapy and CAR-T Cell Therapy performed?

The method of administering Immunotherapy or CAR-T Cell Therapy depends on the specific cancer, the type of therapy chosen, and the patient's overall health.

For CAR-T Cell Therapy:

  • Cell Collection (Apheresis): T-cells are collected from the patient's blood using an apheresis machine, similar to blood donation.
  • Cell Engineering: These T-cells are then sent to a specialized laboratory where they are genetically modified to produce CARs. This process takes several weeks.
  • Cell Expansion: The engineered CAR-T cells are grown in large numbers in the lab.
  • Lymphodepleting Chemotherapy: Patients typically receive a short course of chemotherapy to reduce existing immune cells, making space for the CAR-T cells.
  • CAR-T Cell Infusion: The expanded CAR-T cells are infused back into the patient, usually as a single intravenous infusion.
  • Monitoring: Patients are closely monitored for side effects such as cytokine release syndrome and neurotoxicity.

For Immunotherapy (General):

  • Diagnosis and Planning: After thorough evaluation, a specific immunotherapy drug or combination is chosen.
  • Administration: Immunotherapy drugs are typically given intravenously as infusions over a set period, often every few weeks.
  • Cycles: Treatment usually involves multiple cycles, with duration varying based on the drug, cancer type, and patient response.
  • Monitoring: Regular follow-up appointments and scans are conducted to assess treatment efficacy and manage potential side effects.

What does the recovery process involve?

Recovery from Immunotherapy and CAR-T Cell Therapy is highly individualized. For CAR-T Cell Therapy, patients typically remain hospitalized for several weeks post-infusion for close monitoring of immediate side effects. After discharge, frequent outpatient follow-ups are crucial for several months to manage delayed complications and assess treatment response. Immunotherapy patients might experience fewer immediate hospital stays but require ongoing monitoring and management of potential immune-related adverse events. Both therapies often involve a period of reduced energy and potential immune suppression. It is essential to follow all medical advice, attend scheduled appointments, and report any new symptoms promptly to ensure a smooth recovery and optimal long-term outcomes.

What are the risks and success rates of these therapies?

  • Cytokine Release Syndrome (CRS): A severe systemic inflammatory response, particularly with CAR-T, requiring intensive management.
  • Neurotoxicity: Neurological side effects like confusion, seizures, or speech difficulties, also more common with CAR-T.
  • Infections: Increased risk due to immune suppression, especially post-CAR-T lymphodepleting chemotherapy.
  • Autoimmune Reactions: The immune system may mistakenly attack healthy tissues with some immunotherapies.
  • Fatigue and Flu-like Symptoms: Common side effects experienced during and after treatment.
  • Infusion Reactions: Allergic-like reactions during drug administration.

The success rates for Immunotherapy and CAR-T Cell Therapy vary significantly based on the type of cancer, its stage, the patient's overall health, and the specific therapy used. CAR-T Cell Therapy has shown remarkable success in specific blood cancers, with remission rates of 40-70% in certain refractory cases. Immunotherapy checkpoint inhibitors have transformed treatment for melanoma, lung cancer, and others, often extending survival significantly for a subset of patients. However, not all patients respond, and some may experience disease progression. Long-term remission is possible for responders, but ongoing monitoring is essential to detect any recurrence. Patients should discuss realistic expectations and potential outcomes with their medical team.

What is the cost of Immunotherapy & CAR-T Cell Therapy in Mumbai?

The cost of advanced cancer treatments like Immunotherapy and CAR-T Cell Therapy in Mumbai is influenced by several factors. These include the specific type of immunotherapy agent or CAR-T product required, the duration of treatment, the hospital chosen, the experience of the treating specialists, the need for intensive care, and the duration of stay. Diagnostic tests, pre-treatment evaluations, and post-treatment recovery care also contribute to the overall expense.

In Mumbai, the estimated cost for Immunotherapy can range from approximately INR 3,00,000 to INR 15,00,000 per cycle, while CAR-T Cell Therapy typically starts from INR 1,50,00,000 and can go higher, depending on the product and complexity.

Cost Comparison: Mumbai vs. Other Global Centers

Mumbai offers a compelling cost advantage without compromising on the quality of care for specialized treatments compared to many Western countries.

Location Immunotherapy (per cycle, USD) CAR-T Cell Therapy (Total, USD)
Mumbai $3,500 - $18,000 $180,000 - $300,000
USA $15,000 - $40,000 $400,000 - $700,000
UK $10,000 - $25,000 $350,000 - $550,000
Singapore $8,000 - $20,000 $250,000 - $400,000
Germany $9,000 - $22,000 $300,000 - $450,000

How Mumbai Supports International Patients

  • Dedicated international patient desk for seamless coordination.
  • Assistance with visa applications and travel arrangements.
  • Arrangement of suitable accommodation for patients and their families.
  • Language interpretation services to facilitate clear communication.
  • Guidance on local transportation and logistical support.
  • Personalized patient support throughout their medical journey.

Essential Documents for Your Treatment Journey in Mumbai

  • Valid passport and visa for entry into India.
  • All relevant medical reports, scans, and biopsy results in English.
  • Referral letter from your treating physician in Nigeria.
  • Proof of financial arrangements for treatment costs.
  • Contact details for emergency contacts.
  • Any existing medication prescriptions and health records.

Preparing for Your Immunotherapy or CAR-T Therapy in Mumbai

  • Follow all dietary and medication instructions given by your doctor.
  • Arrange travel and accommodation well in advance.
  • Ensure all necessary medical documents are organized and easily accessible.
  • Discuss potential support systems for your stay with family or caregivers.
  • Understand the treatment plan and ask any questions before arrival.
  • Plan for sufficient funds to cover all medical and living expenses.

Navigating Recovery and Aftercare for Your Journey

  • Adhere strictly to post-treatment medication schedules and lifestyle recommendations.
  • Attend all scheduled follow-up appointments and monitoring tests.
  • Maintain close communication with your medical team for any concerns.
  • Gradually resume activities as advised by your healthcare provider.
  • Be aware of potential side effects and know when to seek immediate medical attention.
  • Plan for a supportive recovery environment, whether in Mumbai or upon returning home.
Ready to take the next step towards advanced cancer treatment? Reach out for a consultation.

Ready to Explore Your Treatment Options in Mumbai?

Your journey towards advanced cancer treatment begins with clear information and dedicated support. Mumbai offers a combination of cutting-edge therapies and compassionate care.

Hospitals Offering this treatment

India offers premium medical procedures at affordable prices. Discover our most popular treatments, delivered by the country's finest doctors.

Meet Our Doctors

Meet our team of highly qualified and experienced medical professionals dedicated to providing the best healthcare services.

Dr. Ajit Singh Baghela

Dr. Ajit Singh Baghela

Consultant

Paediatric Neurology

Haryana

9+ Years

Experience

Artemis Hospital

Hospital

1500

Fees

View Details
Dr. Shelly Mittal

Dr. Shelly Mittal

Sr. Consultant

Medical Oncology & Hematology

New Delhi

14+ Years

Experience

Artemis Hospital

Hospital

1500

Fees

View Details
Dr. Nakul Sinha

Dr. Nakul Sinha

Chairman - Cardiology

Cardiology

New Delhi

41+ Years

Experience

Max Hospital,Gurgaon

Hospital

1500

Fees

View Details
Dr. Hari Goyal

Dr. Hari Goyal

Director

Medical Oncology & Haemato-Oncology

New Delhi

34+ Years

Experience

Apolo Delhi

Hospital

1500

Fees

View Details

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