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Preimplantation Genetic Testing (PGT) Treatment in India

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Preimplantation Genetic Testing (PGT) Treatment in India | Medical Scope & Care

Preimplantation Genetic Testing (PGT) is an advanced reproductive technique. It screens embryos created during in vitro fertilization (IVF) for genetic abnormalities. This testing aims to identify chromosomal defects or single gene disorders. PGT helps improve IVF success rates. It also reduces the risk of transmitting inherited conditions. Couples seeking to ensure healthy pregnancies often consider this option.

Patients from various countries choose Preimplantation Genetic Testing (PGT) Treatment in India. Many from regions like the UAE, Nigeria, Kenya, Bangladesh, and Nepal travel for care. India offers advanced PGT technology at a more accessible cost. The country's fertility clinics provide world-class expertise. Patients benefit from experienced specialists. High success rates also draw international visitors.

India’s medical infrastructure is highly developed. It boasts state-of-the-art fertility centers. These centers are equipped with the latest genetic testing labs. A large pool of skilled embryologists and geneticists is available. India maintains high patient care standards. This ensures comprehensive support throughout the PGT process. The focus remains on patient safety and successful outcomes.

Indications for PGT Treatment

  • Advanced maternal age (typically over 35).
  • History of recurrent miscarriages.
  • Previous IVF failures.
  • Family history of chromosomal abnormalities.
  • Known carriers of single gene disorders.
  • Presence of structural chromosomal rearrangements in parents.
  • Severe male factor infertility cases.

Types of Preimplantation Genetic Testing (PGT)

There are distinct types of PGT, each addressing specific genetic concerns. Understanding these helps in selecting the most appropriate testing method.

PGT-A (for Aneuploidy)

PGT-A screens embryos for chromosomal aneuploidies. Aneuploidy refers to an abnormal number of chromosomes. This condition is a leading cause of miscarriage and IVF failure. Testing helps select embryos with the correct chromosome count. This improves implantation and live birth rates.

PGT-M (for Monogenic Disorders)

PGT-M identifies specific single gene defects. These defects cause conditions like cystic fibrosis or sickle cell anemia. It is offered to couples who are known carriers of a monogenic disorder. This ensures only unaffected embryos are transferred. The risk of passing on the disease is significantly reduced.

PGT-SR (for Structural Rearrangements)

PGT-SR is for couples carrying balanced chromosomal translocations or inversions. These parents are often healthy themselves. However, they risk producing embryos with unbalanced chromosome sets. PGT-SR helps select embryos with a normal or balanced chromosomal complement. This reduces miscarriage risk and improves pregnancy outcomes.

Clinical Evaluation for PGT

  • Comprehensive medical history and physical examination.
  • Detailed genetic counseling for both partners.
  • Carrier screening tests to identify genetic risks.
  • Ovarian reserve testing for the female partner.
  • Semen analysis for the male partner.
  • Infectious disease screening.
  • Pre-IVF hormonal blood tests.

The PGT Procedure Explained

The Preimplantation Genetic Testing (PGT) process begins with standard IVF treatment. Ovarian stimulation produces multiple eggs. These eggs are then fertilized in the lab to create embryos. The embryos develop for several days. A few cells are carefully removed from each embryo (embryo biopsy). This procedure is performed by skilled embryologists. The biopsied cells are sent for genetic analysis. Meanwhile, the embryos are cryopreserved. Results from the genetic testing identify healthy, viable embryos. Only these genetically screened embryos are then selected for uterine transfer. This targeted approach enhances pregnancy success.

Recovery Process and Expectations

The recovery process for PGT primarily aligns with the IVF cycle itself. Physical recovery after egg retrieval is usually short. Patients might experience mild discomfort or bloating for a day or two. After embryo transfer, normal activities can generally resume. There are no specific physical recovery requirements directly from the PGT lab work. Emotional well-being support is crucial. The wait for PGT results can be emotionally challenging. Clinics in India provide counseling and patient support services.

Potential Risks Associated with PGT

  • Possible damage to the embryo during biopsy, though rare.
  • Risk of misdiagnosis, either false positive or false negative.
  • No viable embryos found after testing, leading to cycle cancellation.
  • Mosaicism, where an embryo contains both normal and abnormal cells.
  • Ethical considerations and psychological stress for couples.

Preimplantation Genetic Testing (PGT) Success Rate in India

The success rates for Preimplantation Genetic Testing (PGT) in India are comparable to global standards. They vary based on several factors. Patient age, embryo quality, and the specific genetic condition play a role. Clinics with advanced labs and experienced specialists typically report higher success. On average, PGT can significantly increase the chances of a healthy pregnancy. It reduces the risk of miscarriage for many couples. Individual consultations provide personalized success rate estimates.

Considering PGT in India? Connect with leading specialists for a personalized assessment.

Cost of Preimplantation Genetic Testing (PGT) in India

The cost of Preimplantation Genetic Testing (PGT) in India is significantly more affordable than in many Western countries. This makes it an attractive option for international patients. Pricing can vary based on the clinic's reputation, technology used, and the extent of testing required. The overall cost includes IVF cycle fees, embryo biopsy, and genetic analysis charges. Below is an estimated cost range.

Procedure Component Estimated Cost Range (USD)
IVF Cycle (excluding PGT) $3,000 - $6,000
PGT-A per embryo (approx.) $300 - $600
PGT-M/PGT-SR (setup + per embryo) $2,000 - $5,000 (setup) + $300 - $600 (per embryo)
Embryo Biopsy $500 - $1,500 (often included in PGT fees)
Cryopreservation of embryos $500 - $1,000

These figures are estimates and can fluctuate. It is always advisable to get a detailed quote from your chosen clinic. Many clinics offer package deals. These may include various aspects of the Preimplantation Genetic Testing (PGT) Treatment in India. Factors like the number of embryos tested or pre-cycle investigations will affect the final price. Choosing specialists for Preimplantation Genetic Testing (PGT) in India ensures quality care at a competitive price point.

Ready to explore PGT options? Request a comprehensive treatment plan tailored to your unique needs.

Preimplantation Genetic Testing (PGT) offers hope to many couples facing fertility challenges. India stands as a reputable destination for this advanced procedure. It combines cutting-edge technology with experienced medical professionals. Patients receive high-quality care at accessible costs. Considering PGT in India means choosing a path toward a healthier pregnancy. It is a decision supported by expertise and compassionate care. Researching your options thoroughly is key. Consulting with fertility specialists is a vital first step.

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