Centres Of Excellence
Our Centres of Excellence bring together multidisciplinary teams to deliver precise diagnosis, advanced treatments, and superior outcomes across a wide spectrum of medical specialties.

OVERVIEW
Pediatric movement disorders represent a complex group of neurological conditions affecting motor control, posture, and voluntary movement in developing children. Treatment mechanisms target disrupted basal ganglia circuits, brainstem networks, or corticospinal pathways through pharmacologic modulation, physical rehabilitation, chemodenervation, and functional neurosurgery. The primary goal of clinical management is to optimize functional motor independence, mitigate pain, support developmental milestones, and prevent secondary musculoskeletal deformities.
PROCEDURE
Management of pediatric movement disorders begins with diagnostic phenomenology classification using video-recorded motor examinations and validated clinical rating scales. Pharmacological management involves precise upward titration of oral neurotransmitter modulators or muscle relaxants. For spasticity or focal dystonia, intramuscular injections of botulinum toxin are administered under ultrasound or electromyographic guidance. Surgical candidates undergo stereotactic neuroimaging for deep brain stimulation lead placement into the globus pallidus internus or lumbar surgical implantation of an intrathecal baclofen pump, followed by ongoing longitudinal device programming and task-specific neurorehabilitation.
BENEFITS
Evidence-based management of pediatric movement disorders offers substantial clinical benefits. Multidisciplinary intervention reduces pathological muscle tone, suppresses distressing involuntary movements, decreases muscle spasms, and alleviates neurogenic pain. Functionally, tailored therapies improve voluntary hand use, gait efficiency, seating tolerance, and personal care independence. Interventions such as continuous intrathecal baclofen delivery or deep brain stimulation have been shown in long-term clinical trials to prevent severe progressive joint contractures, decrease hospitalizations for dystonic crises, and significantly enhance overall health-related quality of life for pediatric patients and their families.
RECOVERY
Recovery timelines vary according to the therapeutic modality employed. Outpatient oral pharmacotherapy titration occurs over several weeks to months to monitor efficacy and side-effect profiles. Localized botulinum toxin injections demonstrate onset within 7 to 14 days, reaching peak response at 4 to 6 weeks and lasting approximately 3 to 4 months before repeat treatment is needed. Surgical procedures, such as intrathecal baclofen pump placement or deep brain stimulation, involve a 2 to 5 day inpatient stay, followed by 4 to 6 weeks of surgical site healing and 6 to 12 months of systematic programming and intensive post-operative physical rehabilitation.
WHAT WE TREAT
Pediatric movement disorder management addresses a broad range of hyperkinetic and hypokinetic motor conditions in infants, children, and adolescents. Specific indications include dystonia (generalized, focal, or segmental), spasticity secondary to cerebral palsy or traumatic brain injury, chorea (such as Sydenham chorea or genetic choreas), myoclonus, ataxia, tremor, functional neurological movement disorders, and complex tic disorders including Tourette syndrome.
PREPARATION
Pre-treatment evaluation requires detailed birth and family histories, standardized motor function scoring (e.g., Gross Motor Function Classification System), brain MRI, genetic panels, and metabolic screening. Candidates for surgical interventions undergo multidisciplinary team review, psychological assessment, baseline functional testing, pre-operative nutritional optimization, and formal instruction on post-operative care and infection prevention protocols.
RISKS
Common low-severity side effects of oral medications include somnolence, fatigue, mood fluctuations, gastrointestinal upset, and transient lightheadedness. Intramuscular chemodenervation may cause localized muscle weakness, pain at the injection site, or transient dysphagia. Surgical interventions carry rare but severe risks, including wound infection, cerebrospinal fluid leaks, hardware malfunction or catheter displacement, intracerebral hemorrhage during electrode placement, and paradoxical worsening of movement or dynamic dysarthria during device programming.
JOURNEY
The clinical pathway begins with a comprehensive neurological evaluation, movement video analysis, neuroimaging, and genetic screening to establish an accurate diagnosis. Once identified, a multidisciplinary team designs a targeted care plan combining physical and occupational therapy with oral medications or localized intramuscular botulinum toxin injections. For complex or pharmacoresistant movement disorders like severe dystonia, patients undergo surgical evaluation for intrathecal baclofen pump implantation or deep brain stimulation. Long-term management requires structured developmental follow-ups, regular physical therapy adjustments, and routine neurosurgical parameter tuning to match the child's physical growth and changing functional needs.
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