Preimplantation Genetic Testing (PGT) Treatment in India

Preimplantation Genetic Testing (PGT) is a medical procedure used to diagnose genetic conditions in embryos before implantation during in vitro fertilization (IVF). It is commonly recommended for couples at risk of passing on genetic disorders or experiencing recurrent pregnancy loss. PGT is considered one of the most effective approaches for improving live birth rates in specific patient groups.

Every year, India receives thousands of international patients from countries such as Ethiopia, Nigeria, the UAE, Oman and neighbouring Asian regions for advanced medical care, including Preimplantation Genetic Testing (PGT). With experienced specialists, structured treatment programs and cost-effective medical care, India has become a preferred global destination.

India is a major centre for Preimplantation Genetic Testing (PGT) due to experienced specialists, advanced diagnostics, regulated clinical protocols and cost-effective care pathways. Patients can find the best Preimplantation Genetic Testing (PGT) treatment in India at many accredited fertility clinics.

1. Indications for Preimplantation Genetic Testing (PGT)

Preimplantation Genetic Testing (PGT) may be recommended in the following situations:

• Couples with a known genetic condition they may pass to their children
• Individuals with a family history of specific genetic diseases
• Couples experiencing recurrent miscarriages or implantation failures
• Women of advanced maternal age seeking IVF treatment
• Couples with chromosomal structural rearrangements
• Progressive symptoms not responding to medication
• Structural or functional abnormalities
• Advanced-stage disease
• Failure of previous treatment or procedures

2. Types of Preimplantation Genetic Testing (PGT) in India

2.1 PGT-A (for Aneuploidy)

This test identifies chromosomal abnormalities, like missing or extra chromosomes, in embryos. It is often used for women of advanced maternal age or those with recurrent implantation failure.

2.2 PGT-M (for Monogenic Disorders)

PGT-M screens for specific single-gene disorders, such as Cystic Fibrosis, Thalassemia, or Huntington's disease. This is for couples known to be carriers of such conditions.

2.3 PGT-SR (for Structural Rearrangements)

This type of PGT detects chromosomal structural rearrangements, like translocations or inversions. It helps couples with a parent carrying such rearrangements to avoid affected pregnancies.

2.4 Advanced or Minimally Invasive Procedures

Advanced PGT techniques involve sophisticated genetic sequencing methods. Embryo biopsy is performed meticulously to ensure minimal impact on embryo viability. Laboratories use next-generation sequencing (NGS) for high accuracy.

3. Pre-Treatment Evaluation

Before performing Preimplantation Genetic Testing (PGT), patients undergo a complete evaluation:

3.1 Laboratory Testing

• CBC
• Kidney/liver function tests
• Coagulation profile
• Hormone levels (e.g., FSH, AMH)

3.2 Imaging Studies

• Pelvic ultrasound to assess reproductive organs
• Hysteroscopy or Saline Infusion Sonography (SIS) for uterine evaluation

3.3 Functional Assessment

• Semen analysis for male partners
• Genetic counseling to assess risks and options
• Condition-specific functional scoring

3.4 Infection Screening

HIV, HBV, HCV, TB and other infections are routinely screened. This ensures patient safety and adherence to clinic protocols.

4. Preimplantation Genetic Testing (PGT) Procedure Overview

The procedure typically includes:

• Pre-operative planning: Detailed genetic counseling and IVF planning.
• Anesthesia assessment: For egg retrieval during the IVF cycle.
• Step-by-step execution of the treatment procedure:
  • Ovarian stimulation to produce multiple eggs.
  • Egg retrieval under sedation.
  • In vitro fertilization (IVF) to create embryos.
  • Embryo culture to the blastocyst stage.
  • Embryo biopsy: A few cells are carefully removed from each embryo.
  • Genetic testing of the biopsied cells in a specialized lab.
  • Selection of genetically normal embryos for transfer.
• Monitoring vital parameters: Throughout the IVF process.
• Completion and closure (for surgeries): Embryo transfer into the uterus.
• Transfer to recovery or ICU: Post-retrieval recovery.

The exact steps depend on the type and complexity of Preimplantation Genetic Testing (PGT).

5. Recovery & Post-Treatment Care

After Preimplantation Genetic Testing (PGT) and embryo transfer, patients receive:

• Vital monitoring.
• Pain management (if needed after egg retrieval).
• Medication protocol, usually hormonal support for implantation.
• Nutrition and mobility guidance.
• Scheduled follow-up visits, including pregnancy testing.
• Imaging and lab tests to evaluate progress.

Recovery duration varies according to the individual and IVF cycle outcomes.

6. Risks & Complications

6.1 Early Complications

• Ovarian Hyperstimulation Syndrome (OHSS) from IVF.
• Bleeding or infection from egg retrieval.
• Damage to the embryo during biopsy (rare).
• Procedure-specific risks.

6.2 Late Complications

• Ectopic pregnancy.
• Multiple pregnancies.
• Emotional distress from unsuccessful cycles.
• Medication-related or structural complications.

7. Success Rates of Preimplantation Genetic Testing (PGT) in India

Success rates depend on the severity of the genetic condition, the complexity of the procedure and the patient’s overall health.

• 1-year outcome: 45% – 60% live birth rate per embryo transfer (varies by age).
• 5-year outcome: Higher cumulative live birth rates over multiple cycles.
• Improved functional recovery for most patients.
• Lower complication rates in high-volume centres.

8. Cost of Preimplantation Genetic Testing (PGT) in Major Indian Cities (2025)

City-wise cost range for Preimplantation Genetic Testing (PGT):

Delhi — ₹2,50,000 – ₹5,00,000

Mumbai — ₹2,80,000 – ₹5,50,000

Bangalore — ₹2,70,000 – ₹5,30,000

Chennai — ₹2,60,000 – ₹5,20,000

Hyderabad — ₹2,40,000 – ₹4,80,000

Kolkata — ₹2,30,000 – ₹4,70,000

Pune — ₹2,50,000 – ₹5,00,000

Gurgaon — ₹2,70,000 – ₹5,40,000

Costs vary due to procedure type, hospital category and specialist expertise. The cost of Preimplantation Genetic Testing (PGT) in India is significantly lower than in many Western countries.

9. India vs USA Cost Comparison

10. Condition-Wise Success & Treatment Options

11. India vs Global Cost Comparison (USD)

12. International Patient Services

• Specialist consultations.
• Remote medical report review.
• Personalized cost estimate.
• Medical visa support.
• Assistance with accommodation.
• Airport transfers.
• Interpreter support.
• Pre-treatment evaluation coordination.
• Post-treatment follow-up planning.
• Digital access to medical records.

13. Required Documentation

• Identity proof.
• Passport (for international patients).
• Previous medical reports.
• Relevant lab results.
• Diagnostic images.
• Treatment consent forms.

14. Pre-Treatment Guidelines

• Complete all evaluations thoroughly.
• Avoid infections and maintain good health.
• Follow all medication instructions for IVF stimulation.
• Follow fasting guidelines before egg retrieval.
• Disclose all ongoing medications and supplements.

15. Post-Treatment Guidelines

• Follow prescribed medications, especially hormonal support.
• Attend scheduled follow-ups and pregnancy tests.
• Maintain good hygiene.
• Follow dietary recommendations for general health.
• Avoid strenuous activity until advised.
• Monitor for warning signs or complications.

16. Why India for Preimplantation Genetic Testing (PGT)?

• High-volume specialist centres with dedicated IVF and genetics departments.
• Internationally trained fertility doctors and embryologists.
• Advanced diagnostics and technology for genetic analysis.
• Regulated treatment protocols adhering to international standards.
• Higher Preimplantation Genetic Testing (PGT) success rate in India, especially in major centres.
• Cost-effective medical care compared to Western countries.

DivinHeal supports international patients in accessing reliable, well-guided and specialist-driven Preimplantation Genetic Testing (PGT) treatment in India through safe and structured medical pathways.