Preimplantation Genetic Testing in Bengaluru for Nigerian Patients
Nigerian couples often face complex decisions when considering advanced reproductive treatments like Preimplantation Genetic Testing (PGT). The uncertainty surrounding access, quality, and specific procedures far from home can be daunting, adding stress to an already emotional journey towards starting a family.
Many choose to explore options beyond their borders, and Bengaluru stands out as a preferred destination. This city offers a harmonious blend of specialized medical expertise and a supportive care environment, attracting those seeking focused attention for sensitive procedures.
Trust in Bengaluru's medical ecosystem is built on a foundation of world-class fertility clinics and highly experienced genetic specialists. The city's infrastructure supports seamless coordination of care, ensuring comprehensive follow-ups and continuous support throughout the treatment process.
Is Bengaluru the right choice for your PGT journey?
What is Preimplantation Genetic Testing (PGT)?
Preimplantation Genetic Testing (PGT) is an advanced reproductive technology used in conjunction with In Vitro Fertilization (IVF). It involves screening embryos for genetic abnormalities before they are implanted into the uterus. This crucial step helps identify embryos free from specific genetic conditions or chromosomal anomalies, significantly increasing the chances of a successful pregnancy and the birth of a healthy baby. PGT offers prospective parents peace of mind, especially when there is a known genetic risk.
Understanding the Types of PGT Available
Different forms of PGT address specific genetic concerns:
- PGT-A (for Aneuploidy): This screens embryos for abnormal numbers of chromosomes, a common cause of miscarriage and IVF failure. It identifies embryos with the correct 46 chromosomes.
- PGT-M (for Monogenic/Single Gene Disorders): Used when one or both parents are known carriers of a specific single gene disorder (e.g., sickle cell anemia, cystic fibrosis). PGT-M identifies embryos that have not inherited the specific gene mutation.
- PGT-SR (for Structural Chromosomal Rearrangements): This is for individuals who carry balanced chromosomal translocations or inversions, which can lead to embryos with unbalanced chromosome sets. PGT-SR helps select embryos with a normal chromosomal structure.
When is Preimplantation Genetic Testing Recommended?
- Advanced maternal age (typically over 35) due to increased risk of chromosomal abnormalities.
- Recurrent miscarriages or previous failed IVF cycles with no clear explanation.
- Previous pregnancies or children affected by a chromosomal abnormality.
- Family history or known carrier status of a single gene disorder.
- Couples with male factor infertility where there is a higher risk of genetic issues.
- Individuals carrying balanced chromosomal rearrangements (translocations, inversions).
What Pre-Treatment Evaluation is Needed for PGT?
- Comprehensive genetic counseling to understand family history and risks.
- Detailed fertility assessment for both partners, including hormone tests and semen analysis.
- Karyotyping for both partners to detect any chromosomal abnormalities.
- Screening for infectious diseases.
- Specific genetic testing (e.g., DNA sequencing) if a monogenic disorder is suspected.
- Uterine assessment for the female partner to ensure a healthy environment for implantation.
How is Preimplantation Genetic Testing Performed?
The PGT procedure is an integral part of an IVF cycle and involves several carefully orchestrated steps.
The process typically includes:
- Ovarian Stimulation and Egg Retrieval: The female partner undergoes medication to stimulate egg production, followed by a minor surgical procedure to retrieve the eggs.
- Fertilization: The retrieved eggs are fertilized with sperm in the laboratory to create embryos. This usually involves IVF or ICSI (Intracytoplasmic Sperm Injection).
- Embryo Biopsy: After a few days of development, when embryos reach the blastocyst stage, a small number of cells are carefully removed from the outer layer of each embryo (trophectoderm). This biopsy is performed by highly skilled embryologists.
- Genetic Analysis: The biopsied cells are sent to a specialized genetics laboratory for analysis. Depending on the PGT type, they are screened for chromosomal abnormalities, specific gene mutations, or structural rearrangements.
- Embryo Transfer: Once the genetic results are available, healthy, euploid embryos (those identified as chromosomally normal and free from targeted genetic disorders) are selected for transfer into the woman's uterus. Unused viable embryos can be cryopreserved.
Understanding the Recovery Process After PGT
Recovery from the PGT process itself is generally tied to the IVF components, specifically egg retrieval and embryo transfer. After egg retrieval, a few days of rest are recommended to manage any mild discomfort. Following embryo transfer, patients are typically advised to take it easy for a day or two before resuming light activities. The waiting period for genetic results can be emotionally challenging, and psychological support is often provided. Post-transfer, monitoring for early pregnancy signs and follow-up appointments with the fertility specialist are essential to ensure a smooth transition.
Potential Risks and Expected Success Rates of PGT
- Minor risk of embryo damage during the biopsy procedure.
- Possibility of no healthy embryos found, leading to treatment cancellation.
- Rare chance of misdiagnosis (false positive or false negative).
- Emotional and psychological stress associated with the IVF and PGT journey.
- Risks associated with the IVF procedure itself, such as Ovarian Hyperstimulation Syndrome (OHSS).
The success rates of PGT are quite encouraging, as it significantly improves the chances of a healthy pregnancy by selecting only the most viable embryos. While success varies based on factors like maternal age, underlying fertility issues, and the number of embryos available, PGT typically leads to higher implantation rates and lower miscarriage rates compared to IVF without PGT. Long-term expectations include a greater likelihood of carrying a pregnancy to term and having a child free from the screened genetic conditions.
Cost of Preimplantation Genetic Testing in Bengaluru
The cost of Preimplantation Genetic Testing in Bengaluru is influenced by several factors, including the specific type of PGT (PGT-A, PGT-M, PGT-SR), the number of embryos requiring biopsy and analysis, the chosen fertility clinic, and the expertise of the genetic laboratory. It's important to note that PGT costs are usually separate from the base IVF cycle cost.
In Bengaluru, the cost for Preimplantation Genetic Testing (excluding the IVF cycle) typically ranges from INR 1,50,000 to INR 3,50,000.
Understanding PGT Costs in Bengaluru
Bengaluru offers highly competitive pricing for PGT without compromising on quality or advanced technology. Below is a comparison of PGT costs (excluding IVF) in Bengaluru against other major global destinations:
| Location |
Estimated PGT Cost (Excluding IVF) |
| Bengaluru, India |
INR 1,50,000 - 3,50,000 |
| United States |
USD 5,000 - 10,000 |
| United Kingdom |
GBP 3,000 - 6,000 |
| Singapore |
SGD 6,000 - 12,000 |
| Australia |
AUD 5,000 - 9,000 |
Ready to Explore PGT Options in Bengaluru?
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Support Services for Your Treatment Journey
- Assistance with medical visa applications and extensions.
- Arrangements for comfortable accommodation near your chosen hospital.
- Local transportation coordination for appointments and travel within the city.
- Professional language interpretation services to ensure clear communication.
- Dedicated patient care coordinators to guide you through every step.
- Help with travel itineraries and arrangements for accompanying family members.
Important Papers Required for Your Medical Visit
- Valid passport and a valid medical visa for India.
- Comprehensive medical reports and diagnostic test results from your home country.
- Referral letter from your local doctor, if available.
- Proof of address and identity.
- Any previous genetic test results or family medical history relevant to PGT.
Preparing for Your Procedure in Bengaluru
- Undergo initial online consultations with Bengaluru specialists to review your case.
- Complete any pre-treatment tests requested by the Indian medical team before travel.
- Organize your travel plans, including flights and accommodation in advance.
- Ensure all necessary documents are in order for your international journey.
- Mentally prepare for the treatment process and discuss any concerns with your medical coordinator.
Recovery and Follow-Up Care Instructions
- Adhere strictly to post-transfer medication protocols prescribed by your fertility specialist.
- Follow specific activity restrictions during the initial recovery period.
- Attend all scheduled follow-up appointments and early pregnancy tests.
- Maintain open communication with your Bengaluru medical team for any queries or concerns.
- Plan for adequate rest and emotional support during the crucial two-week wait for pregnancy results.
Take Your Next Step Toward Building Your Family
Contact us to learn how Bengaluru's fertility experts can support your PGT journey.
Begin Your Path to Parenthood with Confidence
Embarking on a PGT journey is a profound decision. In Bengaluru, you will find compassionate care, cutting-edge technology, and experienced specialists ready to support you.