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Preimplantation Genetic Testing (PGT) Treatment in Pune for Bangladesh

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Preimplantation Genetic Testing (PGT) in Pune for Bangladeshi Patients

Bangladeshi patients considering Preimplantation Genetic Testing (PGT) often face concerns about accessibility and quality of advanced fertility treatments locally. The journey to ensure a healthy pregnancy, especially with genetic considerations, can feel overwhelming. Many seek reliable options outside their home country for peace of mind and specialized care.

Pune, India, has emerged as a preferred destination for such specialized care. Its reputation for advanced medical infrastructure and patient-centric approaches draws international patients. People choose Pune for its established medical community and streamlined coordination for those seeking complex fertility solutions like PGT.

Hospitals in Pune house highly skilled fertility specialists and geneticists experienced in PGT. These facilities offer state-of-the-art laboratories crucial for accurate genetic analysis. Patients can expect comprehensive support, including easy follow-ups and integrated care pathways within the city, ensuring continuity of care.

Pune provides a well-regarded environment for Preimplantation Genetic Testing, ensuring expert medical support and advanced technology.

What is Preimplantation Genetic Testing (PGT)?

Preimplantation Genetic Testing, or PGT, is a specialized procedure performed during in vitro fertilization (IVF) to analyze embryos for genetic abnormalities before they are transferred to the uterus. This advanced screening helps identify embryos free from specific genetic conditions or chromosomal anomalies. It involves taking a small biopsy from an embryo developed in the lab and testing the cells for genetic health. PGT aims to improve the chances of a successful pregnancy and the birth of a healthy baby, particularly for couples at higher risk of passing on genetic disorders.

Types of PGT Available

There are different forms of PGT, each designed to detect specific genetic issues:

  • PGT-A (Aneuploidy): Screens embryos for chromosomal abnormalities, such as an extra or missing chromosome (e.g., Down syndrome). This is most common for patients with advanced maternal age or recurrent implantation failure.
  • PGT-M (Monogenic/Single Gene Defects): Identifies embryos carrying a specific gene mutation responsible for an inherited single-gene disorder (e.g., cystic fibrosis, sickle cell anemia, Huntington's disease). This requires prior identification of the specific gene mutation in the parents.
  • PGT-SR (Structural Rearrangements): Detects embryos with chromosomal structural rearrangements, like translocations or inversions, inherited from a parent. This helps prevent miscarriage and the birth of a child with an unbalanced chromosomal abnormality.

When is PGT Recommended?

  • Advanced maternal age (typically over 35) to screen for aneuploidy.
  • History of recurrent miscarriages due to chromosomal issues.
  • Previous IVF cycles with implantation failure.
  • One or both partners are carriers of a single gene disorder.
  • One or both partners have a known chromosomal structural rearrangement.
  • Severe male factor infertility.
  • Couples who wish to reduce the risk of passing on a known genetic condition.

Pre-Treatment Evaluation for PGT

  • Comprehensive fertility assessment for both partners, including hormone tests and semen analysis.
  • Genetic counseling to review family history and determine the most appropriate type of PGT.
  • Karyotyping for both partners to identify any chromosomal structural rearrangements.
  • Specific genetic testing for parents to identify mutations for PGT-M, if applicable.
  • Pre-IVF screening, including infectious disease panel and uterine evaluation.

How Preimplantation Genetic Testing is Performed

The PGT procedure is an integral part of an IVF cycle. The specific steps involved ensure careful handling and analysis of embryos.

Step 1: Ovarian Stimulation and Egg Retrieval

The female partner undergoes controlled ovarian stimulation using fertility medications to produce multiple eggs. These eggs are then retrieved during a minor surgical procedure called ovum pick-up.

Step 2: Fertilization (IVF or ICSI)

The retrieved eggs are fertilized with sperm in the laboratory to create embryos. This can be done through conventional IVF or Intracytoplasmic Sperm Injection (ICSI), where a single sperm is injected into each egg.

Step 3: Embryo Culture

The fertilized embryos are cultured in the laboratory for several days, typically until they reach the blastocyst stage (day 5 or 6). This is the optimal stage for embryo biopsy.

Step 4: Embryo Biopsy

A highly skilled embryologist carefully removes a few cells (trophectoderm cells) from each healthy-looking blastocyst. This biopsy is a delicate procedure performed under a microscope, with minimal impact on the embryo's development.

Step 5: Genetic Analysis

The biopsied cells are sent to a specialized genetics laboratory for analysis. Depending on the type of PGT, the cells are screened for chromosomal aneuploidies, specific gene mutations, or structural rearrangements. The embryos are typically frozen while awaiting test results.

Step 6: Embryo Transfer

Once the genetic test results are available, healthy embryos identified as genetically normal are selected for transfer into the female partner's uterus. This procedure is similar to a standard IVF embryo transfer, aiming for successful implantation and pregnancy.

Recovery Process After PGT and Embryo Transfer

The recovery process primarily relates to the IVF cycle components of egg retrieval and embryo transfer. After egg retrieval, patients may experience mild discomfort, cramping, or bloating for a few days. Rest and avoiding strenuous activities are recommended. Following embryo transfer, patients are typically advised to take it easy, avoid heavy lifting, and refrain from intercourse for a period. Most daily activities can be resumed within a day or two. Regular follow-up appointments, often involving blood tests to check hormone levels and pregnancy status, are crucial. Emotional support and stress management are also important aspects of the recovery journey.

Risks and Success Rates of PGT

  • Minor risks from the IVF process, such as ovarian hyperstimulation syndrome (OHSS) from fertility medications.
  • Potential for damage to the embryo during the biopsy procedure, though this risk is very low in experienced hands.
  • Possibility of no healthy embryos being found for transfer, leading to disappointment.
  • Misdiagnosis (false positive or false negative) of genetic results, though rare, can occur.
  • The success rate of PGT leading to a live birth is tied to the success rates of IVF, which vary based on patient age and overall fertility health.

PGT significantly increases the chances of a successful pregnancy and a healthy live birth for couples at risk. Success rates vary depending on factors like maternal age, underlying fertility issues, and the specific genetic condition being screened. While PGT improves embryo selection, it does not guarantee a pregnancy or a baby free from all conditions. Long-term expectations include a reduced risk of miscarriage and a higher likelihood of a healthy pregnancy, offering families greater confidence.

Considering PGT?

Our specialists in Pune can guide you through the process. Reach out to understand if PGT is the right option for your family planning.

Cost of Preimplantation Genetic Testing (PGT) in Pune

The cost of PGT in Pune is influenced by several factors, including the reputation and facilities of the hospital, the experience of the fertility specialist and geneticists, the specific type of PGT required (PGT-A, PGT-M, or PGT-SR), the number of embryos being tested, and the technology used by the genetics lab. Additionally, preparatory diagnostic tests and associated IVF cycle costs contribute to the overall expense.

In Pune, the approximate cost for Preimplantation Genetic Testing (PGT), excluding the IVF cycle, can range from INR 1,50,000 to INR 3,50,000 per cycle, depending on the number of embryos and specific tests.

PGT Cost in Pune Compared Globally

Pune offers PGT at a fraction of the cost found in many Western countries, without compromising on quality or advanced technology. This makes it an attractive option for international patients seeking high-quality fertility solutions.

Location Approximate PGT Cost (USD)
Pune, India $1,800 – $4,200
Thailand $3,500 – $7,000
UAE $4,000 – $8,500
United Kingdom $6,000 – $12,000
United States $8,000 – $15,000

Assistance Available for International Patients

  • Dedicated international patient desk for seamless coordination and communication.
  • Visa assistance and guidance for medical travel to Pune.
  • Airport transfers and accommodation arrangements based on patient preferences.
  • Language interpretation services to ensure clear understanding between patients and medical staff.
  • Support for local travel and sightseeing during your stay.
  • Assistance with post-treatment follow-up appointments and medication coordination.

Required Papers for Your Medical Visit

  • Valid passport and medical visa for entry into India.
  • Comprehensive medical history records, including previous fertility treatments and genetic test results.
  • Relevant diagnostic reports and specialist consultations related to your condition.
  • Copies of any marriage certificates or identification documents for both partners.
  • Consent forms for treatment, which will be provided by the hospital.

Preparing for Your PGT Procedure

  • Follow all pre-treatment dietary and medication instructions provided by your fertility specialist.
  • Arrange for comfortable travel and accommodation in Pune well in advance.
  • Ensure all necessary documents are prepared and easily accessible for your arrival.
  • Undergo any final screening tests or consultations scheduled upon your arrival in Pune.
  • Maintain open communication with your medical coordinator for any last-minute questions or preparations.

Recovery and Follow-Up Care After PGT

  • Adhere strictly to post-embryo transfer instructions regarding rest and activity restrictions.
  • Take prescribed medications as directed by your doctor to support potential pregnancy.
  • Attend all scheduled follow-up appointments in Pune, including blood tests for pregnancy confirmation.
  • Maintain a healthy lifestyle with balanced nutrition and avoidance of stress.
  • Communicate any unusual symptoms or concerns with your medical team promptly.
  • Plan for continued remote support and guidance from your Pune specialists upon returning home.

Begin Your PGT Journey in Pune

Connect with Pune's leading fertility experts for a personalized consultation. Take the first step towards a healthy future for your family.

Ready to Explore Your Options?

Considering PGT in Pune offers a path to addressing complex genetic concerns with expert care. Access advanced treatments and support designed for your family's unique needs.

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